Postdoctoral researcher in Cryoelectron Microscopy 100 %
The research group headed by Prof. Martin Jinek at the University of Zurich, Switzerland, is looking for a talented, goal-driven and team-oriented postdoctoral researcher with a strong background in single-particle cryoelectron microscopy. Research in the Jinek laboratory is focused on studying the molecular structures and mechanisms of CRISPR-Cas and related bacterial defense systems, as well as eukaryotic mRNA processing machineries. These biological questions are investigated using an integrative approach combining structural biology (Cryo-EM and X-ray crystallography), biochemical and biophysical experiments, and functional studies in cell-based models. The Jinek lab is one of the core users and has regular access to a brand-new FEI Titan Krios (equipped with a K3 camera) in the UZH Department of Biochemistry and Center for Microscopy and Image Analysis.
The postdoctoral researcher will manage and conduct his/her own independent research project within the main research focus areas of the host laboratory. The researcher will also be expected to contribute expertise in single-particle cryo-EM in support of ongoing collaborative projects in the laboratory, closely interacting with PhD students and other postdoctoral researchers in the group. The laboratory has several exciting collaborative projects that would provide excellent training opportunities in complementary structural biology approaches such as X-ray crystallography or biochemical studies.
Interested candidates should have hands-on experience in cryo-EM sample preparation and expertise in processing single-particle data. Experience with biochemical methods, especially protein expression and purification in bacteria and insect cells would be an advantage. The applicants must hold a PhD in structural biology, biochemistry, or a related field, and have a strong research track record.
What we offer
We offer a competitive employment package, a supportive and highly collaborative working environment that fosters academic career development, excellent research funding and state-of-the-art infrastructure for structural biology, biochemistry and biophysics. Zurich is a major European research hub that also offers an exceptionally high quality of life.