PhD Student Position in Chemical Biology of Riboswitches 60 %
The following project will be conducted at the laboratory of Prof. Dr. Roland K.O. Sigel at the Department of Chemistry, University of Zurich, and will be supervised by himself and Dr. Sofia Gallo.
Research of the Sigel group focuses on RNA dynamics and structure, specifically looking at the role of metal ions and/or metal complexes during RNA folding. The molecules under investigation include large ribozymes, G-quadruplexes and riboswitches. For the study of these RNAs, our group employs and develops a wide range of methods that include chemical biology, structural biology (NMR and crystallography), single molecule fluorescent spectroscopy (smFRET) and Molecular Dynamics. The project focuses on the study of riboswitches by chemical biology tools, although the field can be extended in any other direction of the above-mentioned techniques.
We are looking for a highly motivated new member of our group. Candidates must have received (or be soon expecting) a Master's degree in chemistry, biochemistry, molecular biology or Life Sciences. Experience in RNA handling is an asset but not required.
What we offer
You will work in a highly interdisciplinary team of chemists, biochemists, biologists, physicists and bioinformaticians and profit from high standard infrastructure as well as excellent working conditions. Your salary and employment are according to regulations of the University of Zurich and the Swiss National Science Foundation.
Place of work
Prof. Dr. Roland K.O. Sigel University of Zurich Department of Chemistry Winterthurerstrasse 190 (Irchel Campus) 8057 Zurich
Start of employment
Employment start date to be mutually agreed. Please submit a motivation letter, your CV and the contact information of at least one reference to Dr. Sofia Gallo, using the 'apply now' button.