Department of Chemistry

PhD Position in Solid-Phase Peptide Synthesis (Industry Collaboration) 80 %

Start of employment ideally as soon as possible, temporary

A PhD position is available in the group of Prof. Dr. Nina Hartrampf at the Department of Chemistry, University of Zurich (Switzerland), in collaboration with the company Novo Nordisk in Måløv, Denmark. The Hartrampf group uses flow chemistry for the chemical synthesis and modification of peptides and proteins. As part of the collaborative project, you will investigate methods to improve peptide synthesis using flow chemistry, high throughput instrumentation, and computational methods. The PhD will be carried out at the University of Zurich, with additional research visits to Novo Nordisk.

We offer an exciting PhD position in a stimulating and challenging environment at the interface of chemistry, automation, and computational analysis. You will be trained in state-of-the-art SPPS technology, organic chemistry, data analysis, and machine learning. With this joint research project, you will be part of an interdisciplinary and international research collaboration.

Your responsibilities

This project combines a variety of disciplines and tools in the broader field of chemical peptide synthesis and computational chemistry. You will design, synthesize and modify amino acids, and will use them in peptide synthesis using our state-of-the-art fully automated synthesis platform, and Novo Nordisk's high throughput facilities. You will be driving the characterization of chemically synthesized peptides using various analytical techniques (UHPLC, LCMS, CD, etc.). You will use various computational methods to analyze and predict synthesis results, in close collaboration with Novo Nordisk.

Your profile

We are looking for a highly motivated, curious and enthusiastic PhD student for a four-year research collaboration between the Hartrampf group (University of Zurich), and Novo Nordisk (Måløv, Denmark). The candidate should hold a Master's degree in chemistry or chemical engineering, and should have expertise in programming (ideally Python). Expertise in peptide chemistry (SPPS), synthetic organic chemistry and machine learning is a plus, but not required. You are adept at working in an open, interdisciplinary, and collaborative environment that you will contribute to with curiosity, scientific agility, self-motivation, and strong communication skills.

Information on your application

Please submit your application before November 15, 2024 as a single pdf (incomplete applications will not be considered).

Your application should contain:
  • letter of motivation
  • curriculum vitae
  • short summary of past research accomplishments
  • transcripts of your academic records from your University, and a copy of your degree
  • contact details of two referees (e.g. your M.Sc. thesis supervisor)

What we offer

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What we offer

Work-Life Balance
  • Flexible working models (such as part-time positions, mobile working, job-sharing)
  • Childcare at the kihz foundation of UZH and ETH


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Learning and Development
  • Wide range of continuing education courses of UZH and the Canton of Zurich
  • Language Center run jointly with ETH Zurich

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Food
  • Food and drinks at reduced prices in the UZH cafeterias
  • Lunch-Check-card with UZH contribution

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Healthcare
  • Special conditions on the Academic Sports Association ASVZ
  • Free seasonal flu vaccinations
  • Rest and relaxation at the quiet room in the university tower

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Discounts
  • Private traffic: Carsharing, rent a vehicle, parking space
  • Digitalization: Hardware, software, mobile phone subscriptions
  • Special conditions on hotel reservations

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Conditions of Employment
  • Policies of the UZH
  • Most UZH staff are employed according to public law


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International Services
  • Support for people from outside Switzerland

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Campuses
  • Campuses Zurich City, Zurich Irchel, Oerlikon and Schlieren
  • Sites Zurich West, Old Botanical Garden, Botanical Garden and Lengg

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Location

Department of Chemistry

Winterthurerstrasse 190, 8057 Zürich, Switzerland

Further information

Questions about the job

Prof. Dr. Nina Hartrampf
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Working at UZH
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!
More → https://www.uzh.ch/cmsssl/en/explore/work.html

Working at UZH

The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer! More
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